Filter By:

Multivalent Exosome based protein vaccine: a “mix and match” approach to epidemic viruses’ challenges.

Mafalda Cacciottolo, Li-En Hsieh, Yujia Li, Michael J. LeClaire, Justin B Nice, Ryan Twaddle, Ciana Mora, Meredith Young, Jenna Angeles, Christy Lau, Cindy Jin, Kristi Elliott, Minghao Sun

View Article

CaCl2 heatshock: A rapid, adjustable and feasible method for loading nucleic acid cargos in 293F exosomes

Mahrou Sadri, Michael LeClaire, Justin Nice, Mafalda Cacciottolo, Cindy Liu, Christy Lau, Stephanie Adachi, Firouz Mohsenian, Meena Murali, Kristi Elliott, Minghao Sun 

View Article

Exosomes engineered with SARS-CoV-2 spike and nucleocapsid proteins induce strong immune response against multiple variants of concern (VOCs)

Justin B Nice, Mafalda Cacciottolo, Yujia Li, Michael J. LeClaire, Ryan Twaddle, Ciana L. Mora, Stephanie Y. Adachi, Esther R. Chin, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun 

View Article

Exosome-Based Multivalent Vaccine: Achieving Potent Immunization, Broadened Reactivity, and Strong T-Cell Responses with Nanograms of Proteins

Mafalda Cacciottolo, Justin B Nice, Yujia Li, Michael J. LeClaire, Ryan Twaddle, Ciana L. Mora, Stephanie Y. Adachi, Esther R. Chin, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun

View Article

Multivalent Exosome based vaccine: a “cocktail” approach to epidemic viruses’ challenges

Mafalda Cacciottolo, LiEn Hsieh, Yujia Li, Justin B Nice, Michael J. LeClaire, Ryan Twaddle, Ciana L. Mora, Stephanie Y. Adachi, Esther R. Chin, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun

View Article

Exosome based multivalent vaccine: achieving potent immunization, broaden reactivity and T cell response with nanograms of proteins without any adjuvant

Mafalda Cacciottolo, Justin B Nice, Yujia Li, Michael J. LeClaire, Ryan Twaddle, Ciana L. Mora, Stephanie Y. Adachi, Esther R. Chin, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun

View Article

Exosome based multivalent vaccine: achieving potent immunization, broadened reactivity, and strong T cell responses with nanograms of proteins.

Mafalda Cacciottolo, Justin B Nice, Yujia Li, Michael J LeClaire, Ryan Twaddle, Ciana L. Mora, Stephanie Y. Adachi, Esther R. Chin, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun

View Article

Exosome-mediated mRNA Delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity

Shang Jui Tsai, Nadia A. Atai, Mafalda Cacciottolo, Justin Nice, Arjang Salehi, Chenxu Guo, Alanna Sedgwick, Saravana Kanagavelu, Stephen J. Gould

View Article

Extracellular Vesicles Derived from Cardiosphere-derived Cells as a Potential Antishock Therapeutic

Chance, Tiffani C. PhD; Wu, Xiaowu MD; Keesee, Jeffrey D. BS; Garcia-Marcano, Josue; Salgado, Christi L. BS; Liu, Bin BS; Moseley, Jennifer J. PhD; Peck, Kiel A. MS; R.-Borlado, Luis PhD; Atai, Nadia A. MD, PhD; Gould, Stephen J. PhD; Marban, Linda S. PhD; Cap, Andrew P. MD, PhD; Rathbone, Christopher R. PhD; Bynum, James A. PhD

View Article

Small molecule inhibitors and culture conditions enhance therapeutic cell and EV potency via activation of beta-catenin and suppression of THY1

Ahmed Gamal-EldinIbrahim Ph.D., MPH, Chang Li BS, Alessandra Ciullo Ph.D. K. Candis Jones-Ungerleider MD, MSE, Kiel Peck BS, Linda Marbán Ph.D, Eduardo Marbán MD, Ph.D

View Article