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Publications

Our Science

Our Science

  • Deramiocel (Biologic Medicine)
  • Exosomes Technology
  • Publications
  • Strategic Partnerships

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Multivalent Exosome Based Protein Vaccine: A “Mix and Match” Approach to Epidemic Viruses’ Challenges

Mafalda Cacciottolo, Li-En Hsieh, Yujia Li, Michael J. LeClaire, Ciana L. Mora, Christy Lau, Charles Dwyer, Kristi Elliott and Minghao Sun

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Treatment with Deramiocel in DMD: Evidence of Long-Term Stabilization in Performance of Upper Limb Function Compared to Matched External Comparators (MDA 2025)

Craig M. McDonald, M.D., Chet Villa, M.D., Cuixia Tian, M.D., Alexander M. Zygmunt, M.D., Nicholas J. Ollberding, Ph.D., Kevin Berth, Upagna Desai, Zena Askerova Ph.D., Nathaniel J. Hogan, Ph.D., Kati S. Maharry, Ph.D., Mark S. Awadalla, Linda Marbán, Ph.D.

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Engineered exosomes loaded with phosphorodiamidate morpholino oligomers targeting mouse exon 23 promote exon skipping in-vitro and in-vivo

Firouz Mohsenian, Meena Murali, Michael LeClaire, Christy Lau, Mafalda Cacciottolo, Kristi Elliott, Minghao Sun

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Multi-modal benefits of deramiocel (CAP-1002) in late-stage patients with DMD: a new treatment approach to target skeletal and cardiac muscle pathogenesis (HOPE 2-OLE trial: 36-month data) (WMS 2024)

Craig M. McDonald, M.D., Chet Villa, M.D., Jonathan H. Soslow, M.D., Cuixia Tian, M.D., Alexander M. Zygmunt, M.D., Nicholas J. Ollberding, Ph.D., Kan N. Hor, M.D., Matthew M. Harmelink, M.D., Arun S. Varadhachary, M.D., Ph.D., Susan Apkon, M.D., Veena Ramanna, Upagna Desai, Nathaniel J. Hogan, Ph.D., Kati S. Maharry, Ph.D., Mark S. Awadalla, Linda Marbán, Ph.D.

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Deramiocel (CAP-1002) Demonstrates Disease Modification in Later-Stage DMD Patients 36-Month Safety and Efficacy Results from the HOPE-2 Open Label Extension (PPMD presentation)

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Exosome-Mediated Intracellular Delivery of Arginase 1: a Potential Application for the Treatment of Arginase-1 Deficiency

Li-En Hsieh, Mafalda Cacciottolo, Michael LeClaire, Christy Lau, Kristi Elliott, Minghao Sun

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Targeted Cargo Delivery to Mouse Lower Limb by Exosomes Carrying a Muscle Targeting Moiety

Minghao Sun, Mafalda Cacciottolo, Yujia Li, Firouz Moshenian, Meena Murali, William Morrison, Michael LeClaire, Kristi Elliott

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Exosomes loaded with siRNA targeting the RRM2 gene trigger apoptosis in the SKOV3 Ovarian Cancer cell-line

Firouz Mohsenian, Meena Murali, Michael LeClaire, Cindy Lau, Kristi Elliot, Minghao Sun

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Long Term Safety and Efficacy of CAP-1002 in late-stage patients with DMD: A New Treatment Approach to Target Skeletal and Cardiac Muscle Pathogenesis (24-Month Data from HOPE-2-OLE Study)

Craig M. McDonald, MD, Suzanne Hendrix, PhD, Michelle Eagle, PhD, Matthew M. Harmelink, MD, Arun S. Varadhachary, MD, PhD, Cuixia Tian, MD, Susan Apkon, MD, Chet Villa, MD, Michael D. Taylor, MD, Kan N. Hor, MD, Mitchell Wassom, MS, Upagna Desai, Mark S. Awadalla, Linda Marbán, PhD

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Targeted ASO Delivery To Mouse Lower Limb by Exosome Carrying A Muscle Targeting Moiety

Minghao Sun, Yujia Li, SunMafalda Cacciottolo, Mahrou Sadri, Michael LeClaire, David Tran, Kristi Elliott,, Linda Marbán

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