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Multivalent Exosome Based Protein Vaccine: A “Mix and Match” Approach to Epidemic Viruses’ Challenges

Mafalda Cacciottolo, Li-En Hsieh, Yujia Li, Michael J. LeClaire, Ciana L. Mora, Christy Lau, Charles Dwyer, Kristi Elliott and Minghao Sun

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Engineered exosomes loaded with phosphorodiamidate morpholino oligomers targeting mouse exon 23 promote exon skipping in-vitro and in-vivo

Firouz Mohsenian, Meena Murali, Michael LeClaire, Christy Lau, Mafalda Cacciottolo, Kristi Elliott, Minghao Sun

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Exosome-Mediated Intracellular Delivery of Arginase 1: a Potential Application for the Treatment of Arginase-1 Deficiency

Li-En Hsieh, Mafalda Cacciottolo, Michael LeClaire, Christy Lau, Kristi Elliott, Minghao Sun

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Targeted Cargo Delivery to Mouse Lower Limb by Exosomes Carrying a Muscle Targeting Moiety

Minghao Sun, Mafalda Cacciottolo, Yujia Li, Firouz Moshenian, Meena Murali, William Morrison, Michael LeClaire, Kristi Elliott

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Exosomes loaded with siRNA targeting the RRM2 gene trigger apoptosis in the SKOV3 Ovarian Cancer cell-line

Firouz Mohsenian, Meena Murali, Michael LeClaire, Cindy Lau, Kristi Elliot, Minghao Sun

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Targeted ASO Delivery To Mouse Lower Limb by Exosome Carrying A Muscle Targeting Moiety

Minghao Sun, Yujia Li, SunMafalda Cacciottolo, Mahrou Sadri, Michael LeClaire, David Tran, Kristi Elliott,, Linda Marbán

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Exosomes: Scalable Production, Purification, and Characterization Methods using 293F Cells

Michael LeClaire, Ph.D, Justin Nice, Ph.D, Yujia Li, Ph.D, Christy Lau, Stephanie Adachi, Ciana Mora, Mafalda Cacciottolo, Ph.D, Kristi Elliott, Ph.D, Minghao Sun, Ph.D

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Nanograms of SARS-CoV-2 spike protein delivered by exosomes induce potent neutralization of both delta and omicron variants

Mafalda Cacciottolo, Yujia Li, Justin B. Nice, Michael J. LeClaire, Ryan Twaddle, Ciana L. Mora, Stephanie Y. Adachi, Meredith Young, Jenna Angeles, Kristi Elliott, Minghao Sun*

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Multivalent Exosome based protein vaccine: a “mix and match” approach to epidemic viruses’ challenges.

Mafalda Cacciottolo, Li-En Hsieh, Yujia Li, Michael J. LeClaire, Justin B Nice, Ryan Twaddle, Ciana Mora, Meredith Young, Jenna Angeles, Christy Lau, Cindy Jin, Kristi Elliott, Minghao Sun

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CaCl2 heatshock: A rapid, adjustable and feasible method for loading nucleic acid cargos in 293F exosomes

Mahrou Sadri, Michael LeClaire, Justin Nice, Mafalda Cacciottolo, Cindy Liu, Christy Lau, Stephanie Adachi, Firouz Mohsenian, Meena Murali, Kristi Elliott, Minghao Sun 

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