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Publications

Our Science

Our Science

  • CAP-1002 (Cell Therapy)
  • Exosomes Technology
  • Publications
  • Strategic Partnerships

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Therapeutic benefits of intravenous cardiosphere-derived cell therapy in rats with pulmonary hypertension

Ryan C. Middleton, Mario Fournier, Xuan Xu, Eduardo Marbán, Michael I. Lewis

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A Comprehensive Method for Identification of Suitable Reference Genes in Extracellular Vesicles

Kenneth Gouina, Kiel Peck, Travis Antes, Jennifer Leigh Johnson, Chang Li, Sharon Denise Vaturi, Ryan Middleton, Geoff de Couto, Ann-Sophie Walravens, Luis Rodriguez-Borlado, Rachel Ruckdeschel Smith, Linda Marbán, Eduardo Marbán and Ahmed Gamal-Eldin Ibrahim

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Reversal of cardiac and skeletal manifestations of Duchenne muscular dystrophy by cardiosphere-derived cells and their exosomes in mdx dystrophic mice and in human Duchenne cardiomyocytes

Aminzadeh M, Rogers R, Gouin K, Fournier M, Tobin R, Guan X, Childers M, Andres A, Taylor D, Ibrahim A, Ding X, Torrente A, Goldhaber J, Victor R, Gottlieb R, Lewis M, Marbán E.

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Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL-10 expression and secretion

Linda Cambier, Geoffrey de Couto, Ahmed Ibrahim, Antonio K Echavez, Jackelyn Valle,
Weixin Liu, Michelle Kreke, Rachel R Smith, Linda Marbán & Eduardo Marbán

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Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction

Romain Gallet, JamesDawkins, Jackelyn Valle, Eli Simsolo, Geoffrey de Couto, Ryan Middleton, EleniTseliou, Daniel Luthringer, Michelle Kreke, Rachel R. Smith, Linda Marbán, Bijan Ghaleh, and Eduardo Marbán

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Macrophages Mediate Cardioprotective Cellular Postconditioning in Acute Myocardial Infarction

Geoffrey de Couto, Weixin Liu, Eleni Tseliou, Baiming Sun, Nupur Makkar, Hideaki Kanazawa,
Moshe Arditi, and Eduardo Marbán

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Commercial Potential as Byproducts of Cell Manufacturing for Research and Therapeutic Use

James A. Smith, Kelvin S. Ng, Benjamin E. Mead, Sue Dopson, Brock Reeve, James Edwards, Matthew J.A. Wood, Andrew J. Carr, Kim Bure, Jeffrey M. Karp, and David A. Brindley

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Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in myocardial repair

Cheng K, Malliaras K, Smith RR, Shen D, Sun B, Blusztajn A, Xie Y, Ibrahim A, Aminzadeh MA, Liu W, Li TS, De Robertis MA, Marbán L, Czer LS, Trento A, Marbán E.

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TCT-152 ALLogeneic Heart STem Cells To Achieve Myocardial Regeneration (ALLSTAR): The Six Month Phase I Safety Results

Raj Makkar; Richard Schatz; Jay H. Traverse; Andrew Hamer; Katherine Beattie; Rachel R. Smith; Frances Kivel; Linda Marban; Eduardo Marban; Timothy D. Henry

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Moving beyond surrogate endpoints in cell therapy trials for heart disease

Malliaras K, Marbán E.

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